Undergraduate Course: Synthetic Organic Chemistry Level 10 (CHEM10024)

Course Outline
School	School of Chemistry	College	College of Science and Engineering
Credit level (Normal year taken)	SCQF Level 10 (Year 4 Undergraduate)	Availability	Available to all students
SCQF Credits	20	ECTS Credits	10
Summary	A lecture course covering contemporary synthetic methods in organic chemistry, and their application to complex molecule synthesis. The course comprises individual lectures courses on: Template-directed Synthesis, Reagents for Organic Synthesis, Solid Phase Synthesis, Organometallics in Synthesis, Pericyclic Reactions and Asymmetric Base Catalysis. Either the Level 10 or Level 11 version of this course (as specified in the degree programme tables) is a compulsory requirement for Year 4/5 students on degrees in Chemistry or Medicinal and Biological Chemistry, but can be taken by Year 4/5 students on any Chemistry degree programme.
Course description	The course contains the 6 lecture courses outlined above, each with an associated small group tutorial. The final examination consists of a total of six questions, one from each of the lecture modules. Students must answer 4 questions from these 6 options.

Entry Requirements (not applicable to Visiting Students)
Pre-requisites	Students MUST have passed: Chemistry 3A (CHEM09005) AND Chemistry 3B (CHEM09006) AND Chemistry 3P Practical and Transferable Skills (CHEM09007)	Co-requisites
Prohibited Combinations	Students MUST NOT also be taking Synthetic Organic Chemistry Level 11 (CHEM11026)	Other requirements	Must include a weighted average of Grade D or higher in Chemistry 3A and Chemistry 3B, at the first attempt; or with the permission of Head of School.

Information for Visiting Students
Pre-requisites	None
High Demand Course?	Yes

Course Delivery Information

Academic year 2015/16, Available to all students (SV1)		Quota: None
Course Start	Semester 1
Timetable	Timetable
Learning and Teaching activities (Further Info)	Total Hours: 200 ( Lecture Hours 30, Seminar/Tutorial Hours 9, Summative Assessment Hours 2.5, Revision Session Hours 6, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 149 )
Assessment (Further Info)	Written Exam 100 %, Coursework 0 %, Practical Exam 0 %
Additional Information (Assessment)	One degree exam of 2.5 hours. (Visiting Student Variant Assessment One degree exam of 2.5 hours at the end of Semester 1.)
Feedback	Each lecture course has an associated tutorial. This will provide students with practice at problem-solving and tackling exam-like questions. It is also an opportunity for students to discuss any issues pertaining to the lecture course. Additional pre-exam revision sessions and/or individual meetings will be offered by the lecturers.
Exam Information
Exam Diet	Paper Name		Hours & Minutes
Main Exam Diet S2 (April/May)			2:30

Academic year 2015/16, Part-year visiting students only (VV1)		Quota: None
Course Start	Semester 1
Timetable	Timetable
Learning and Teaching activities (Further Info)	Total Hours: 200 ( Lecture Hours 30, Seminar/Tutorial Hours 9, Summative Assessment Hours 2.5, Revision Session Hours 6, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 149 )
Assessment (Further Info)	Written Exam 100 %, Coursework 0 %, Practical Exam 0 %
Additional Information (Assessment)	One degree exam of 2.5 hours. (Visiting Student Variant Assessment One degree exam of 2.5 hours at the end of Semester 1.)
Feedback	Each lecture course has an associated tutorial. This will provide students with practice at problem-solving and tackling exam-like questions. It is also an opportunity for students to discuss any issues pertaining to the lecture course. Additional pre-exam revision sessions and/or individual meetings will be offered by the lecturers.
Exam Information
Exam Diet	Paper Name		Hours & Minutes
Main Exam Diet S1 (December)			2:30

Learning Outcomes
On completion of this course, the student will be able to: To recognise and understand the principles behind various pericyclic reactions, such as cycloadditions, electrocyclic reactions, sigmatropic rearrangements and group transfer reactions. To be able to use Frontier Molecular Orbital Theory (underpinned by the concept of Conservation of Orbital Symmetry) to analyze pericyclic reactions. To understand the chemistry and applications of a range of boron, phosphorus, silicon, sulfur and selenium reagents in modern organic synthesis. To appreciate and explain the use of organic and main-group nucleophilic catalysts, and how these can be applied to the construction of asymmetric organic molecules. To understand the use of solid phase organic methods as applied to peptide synthesis. To appreciate the role that solid phase organic synthesis plays in the pharmaceutical industry, particularly with respect to the use of combinatorial chemistry in screening against biological targets. To understand the principles and uses of modern organometallic methods in organic synthesis, including both stoichiometric and catalytic procedures. To understand the synthesis of topologically non-trivial and functional organic molecules using concepts from supramolecular chemistry. To be able to describe the principles behind molecular switches, motors, shuttles and other 'designer' molecules.

Reading List
"Organic Chemistry", Clayden, Greeves, Warren and Wothers, Oxford Press. Additional reading material for each module will be provided by the course lecturer in lecture 1 of each course.

Additional Information
Graduate Attributes and Skills	Not entered
Additional Class Delivery Information	30 hours lectures + 6 hours tutorials, at times arranged.
Keywords	SOC(L10)