Postgraduate Course: High Throughput Drug Discovery (PGBI11077)

Course Outline
School	School of Biological Sciences	College	College of Science and Engineering
Credit level (Normal year taken)	SCQF Level 11 (Postgraduate)
Course type	Online Distance Learning	Availability	Not available to visiting students
SCQF Credits	10	ECTS Credits	5
Summary	Online Distance Learning Course The focus of high throughput screening in drug discovery has been on automating assay techniques so that large libraries of molecules could be screened against disease relevant targets. Over time, this has developed to include a wide array of assay and screening technologies to provide a broad range of parameters and physiologically relevant information. The ultimate aim in this area is to reduce the screening costs per compound allowing routine screening of large libraries in an assay method appropriate to the drug target.
Course description	Not entered

Entry Requirements (not applicable to Visiting Students)
Pre-requisites		Co-requisites
Prohibited Combinations		Other requirements	None

Course Delivery Information

Academic year 2017/18, Not available to visiting students (SS1)		Quota: None
Course Start	Semester 1
Course Start Date	06/11/2017
Timetable	Timetable
Learning and Teaching activities (Further Info)	Total Hours: 100 ( Online Activities 20, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 78 )
Assessment (Further Info)	Written Exam 0 %, Coursework 100 %, Practical Exam 0 %
Additional Information (Assessment)	50 % group assessment (including maximum 20% variation for Peer Assessment of contribution) 50 % electronic portfolio comprising learning log and contribution to Skills Profile
Feedback	Not entered
No Exam Information

Learning Outcomes
On completion of this course, the student will be able to: Understand the basics of assay design for use in large scale multiwell robotic screening environments Be aware of the issues of reproducibility and false positive/negative signal generation in these types of assay platforms. Describe the principles of combinatorial chemistry as applied to the drug discovery process. Show an understanding of the various screening techniques and assay methods currently used in drug discovery Analyse high throughput screening data and calculate the Zż value to indicate assay quality.