THE UNIVERSITY of EDINBURGH

DEGREE REGULATIONS & PROGRAMMES OF STUDY 2017/2018

University Homepage
DRPS Homepage
DRPS Search
DRPS Contact
DRPS : Course Catalogue : School of Biological Sciences : Postgraduate

Postgraduate Course: Measuring Drug Binding (PGBI11071)

Course Outline
SchoolSchool of Biological Sciences CollegeCollege of Science and Engineering
Credit level (Normal year taken)SCQF Level 11 (Postgraduate) AvailabilityNot available to visiting students
SCQF Credits10 ECTS Credits5
Summary**Online Distance Learning Course**

A core competency in Drug Discovery is to appreciate how to measure drug binding quantitatively, in order to assess derivatives of a ¿lead¿ compound that bind more tightly. There are common pitfalls in the interpretation of these numbers, which are inadequately appreciated by many. The course is designed to introduce students to concepts and nomenclature in quantitating drug binding. A common technique involving fluorescence quenching will be used for illustration. Students will fit experimental data using a variety of models and use statistical techniques to distinguish between them. Concepts of over- and under-fitting data, and correlation of parameters will be illustrated, as well as confounding artefacts that affect biophysical techniques.
Course description Not entered
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Course Delivery Information
Academic year 2017/18, Not available to visiting students (SS1) Quota:  None
Course Start Semester 1
Course Start Date 18/09/2017
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 100 ( Online Activities 20, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 78 )
Assessment (Further Info) Written Exam 0 %, Coursework 100 %, Practical Exam 0 %
Additional Information (Assessment) 50% = Group Assessment (including maximum 20% variation for Peer Assessment of contribution)

50% = Electronic Portfolio (comprising of learning log and contribution to skills profile)
Feedback Not entered
No Exam Information
Learning Outcomes
On completion of this course, the student will be able to:
  1. Demonstrate advanced knowledge of concepts applied to measuring drug binding;
  2. Acquire the ability to use common software to fit experimental data and to extend this into unknown situations;
  3. Show an appreciation of under- and over-fitting experimental data and be able to use statistical methods to demonstrate either;
  4. Show awareness in the literature of common pitfalls in measuring drug binding ;
  5. Have acquired a critical faculty regarding potential artifacts in biophysical techniques.
Reading List
None
Additional Information
Graduate Attributes and Skills Not entered
KeywordsMDB
Contacts
Course organiserDr Paul Mclaughlin
Tel: (0131 6)50 7060
Email:
Course secretaryMrs Claire Black
Tel: (0131 6)50 8637
Email:
Navigation
Help & Information
Home
Introduction
Glossary
Search DPTs and Courses
Regulations
Regulations
Degree Programmes
Introduction
Browse DPTs
Courses
Introduction
Humanities and Social Science
Science and Engineering
Medicine and Veterinary Medicine
Other Information
Combined Course Timetable
Prospectuses
Important Information
 
© Copyright 2017 The University of Edinburgh - 6 February 2017 8:53 pm