Undergraduate Course: Biomacromolecules Level 11 (CHEM11043)
Course Outline
| School | School of Chemistry |
College | College of Science and Engineering |
| Course type | Standard |
Availability | Available to all students |
| Credit level (Normal year taken) | SCQF Level 11 (Year 4 Undergraduate) |
Credits | 20 |
| Home subject area | Chemistry |
Other subject area | None |
| Course website |
None |
Taught in Gaelic? | No |
| Course description | A course of lectures and a workshop covering synthesis, chemistry, structure, function and engineering of biological polymers. The course will teach how biopolymers are constructed from simple building blocks, and folded into three-dimensional structures. The ability of biomacromolecules to dynamically and specifically interact and cooperate with one another, on a range of timescales and affinities, will be discussed. The course will also cover production of modified or engineered biomacromolecules. Chemical complexity and functional capabilities arising from prosthetic groups, cofactors, metal ions and post-translational modifications will be described as will the ability of proteins to act as molecular wires and biological catalysts. The taught material will include components on protein manufacture and validation, protein and nucleic acid chemistry, enzymology, metalloproteins, and the role of proteins in cellular electrochemistry.
Either the Level 10 or Level 11 version of this course version of this course (as specified in the degree programme tables) is a compulsory requirement for Year 4/5 students on degrees in Medicinal and Biological Chemistry, but can be taken by Year 4/5 students on any Chemistry degree programme.
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Information for Visiting Students
| Pre-requisites | None |
| Displayed in Visiting Students Prospectus? | No |
Course Delivery Information
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| Delivery period: 2012/13 Semester 1, Available to all students (SV1)
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Learn enabled: Yes |
Quota: None |
| Location |
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Description |
Weeks |
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| No Classes have been defined for this Course |
| First Class |
First class information not currently available |
| Exam Information |
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| Main Exam Diet S2 (April/May) | | 3:00 | | |
Summary of Intended Learning Outcomes
Upon completion of this course students should be able to:
- explain the biosynthesis as well as the laboratory-based manufacture and purification of biologically important polymers.
- appreciate how knowledge of macromolecular 3D structure illuminates the understanding of mechanism and how (with examples) "form follows function".
- understand, through the study of examples, the principles of molecular recognition and cooperation, molecular crowding and self-assembling multiprotein complexes.
- understand the concepts of molecular machines and molecular wires, with an emphasis on chemical mechanisms, thermodynamics and electrochemistry.
- recognize the fundamental principles underlying the structure, function and dynamics of biomacromolecules.
Learning outcomes specific to attainment of a pass at Level 11 include:
- ability to integrate all, or most, of the main areas of the course
- development of original and creative responses to problems and issues within the course
- application of critical analysis, evaluation and synthesis to issues at the forefront of the subject area
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Assessment Information
| One 3 hour degree exam. |
Special Arrangements
| None |
Additional Information
| Academic description |
Not entered |
| Syllabus |
Not entered |
| Transferable skills |
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| Reading list |
Not entered |
| Study Abroad |
Not entered |
| Study Pattern |
Not entered |
| Keywords | Not entered |
Contacts
| Course organiser | Prof Paul Barlow
Tel: (0131 6)50 4727
Email: Paul.Barlow@ed.ac.uk |
Course secretary | Ms Sarah Mcneil
Tel: (0131 6)50 4707
Email: Sarah.F.McNeil@ed.ac.uk |
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© Copyright 2012 The University of Edinburgh - 31 August 2012 3:42 am
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