Lab-on-Chip Technologies (P03068)

? Credit Points : 10 ? SCQF Level : 11 ? Acronym : EEL-P-P03068

This module will outline the basic concept of devices that integrate one or several laboratory functions on a single chip, and how they can offer advantages specific to their application. Such advantages include: low fluid volumes that lead to lower reagent costs and smaller biological samples for diagnostic purposes; faster analysis and response times that also provide better process control; the ability through parallel processing to provide high-throughput screening; and inherent low fabrication costs that make disposable chips economically viable. The influence of the scaling-down of dimensions on the physico-chemical behaviour of fluids and chemical reactions will also be covered. Current applications of lab-on-chip devices will be given.

? Keywords : Biochemical assays, dielectrophoresis, electrophoresis, electroosmosis, high-throughput screening, MEMS devices, microfluidics, micro total analysis systems (TAS), non-dimensional parameters, point-of-care testing, real-time PCR, single-cell analysis.

Entry Requirements

? This course is not available to visting students.

Subject Areas

Home subject area

Postgraduate (School of Engineering and Electronics), (School of Engineering and Electronics, Schedule M)

Delivery Information

? Normal year taken : Postgraduate

? Delivery Period : Not being delivered

? Contact Teaching Time : 1 hour(s) 40 minutes per week for 10 weeks

All of the following classes

Type	Day	Start	End	Area
Lecture	Sunday	09:00	09:50	KB

Summary of Intended Learning Outcomes

An appreciation of the design and development of microfluidic devices that can perform many, if not all, of the functions typically associated with full-scale automated biochemical analysis devices containing pumps, mixers, heat elements, read-out electronics, etc. An understanding of how to avoid the requirement of external power sources or instrumentation by incorporating into these devices the inherent properties of the fluid and its microenvironment (capillary force, evaporation, wicking, heat transfer, diffusion, etc.) for fluid movement, mixing, heating, cooling, and catalyzing chemical reactions. An understanding of how to apply non-dimensional parameters (e.g., Knudsen, Peclet, Reynolds number) to practical flow problems.