Synthetic Organic Chemistry Level 10 (VS1) (U02999)

? Credit Points : 20 ? SCQF Level : 10 ? Acronym : CHE-4-VSynOrg10

A lecture course covering contemporary synthetic methods in organic chemistry, and their application to complex molecule synthesis. The course comprises individual lecture courses on: Reagents for Organic Synthesis, Synthesis of Natural Products, Solid Phase Synthesis, Synthesis of Unnatural Products, Pericyclic Reactions, Organometallics in Synthesis.

Entry Requirements

? This course is only available to part year visiting students.

? This course is a variant of the following course : U01245

? Pre-requisites : Must be visiting undergraduate student.

? Prohibited combinations : Synthetic Organic Chemistry Level 11 (CHE-4-SynOrg11). Synthetic Organic Chemistry Level 10 (CHE-4-SynOrg10).

Subject Areas

Home subject area

Chemistry, (School of Chemistry, Schedule L)

Delivery Information

? Normal year taken : 4th year

? Delivery Period : Semester 1 (Blocks 1-2)

? Contact Teaching Time : 3 hour(s) per week for 10 weeks

First Class Information

Date	Start	End	Room	Area	Additional Information
18/09/2007	09:00	09:50	Lecture Theatre 100, Joseph Black Building	KB

All of the following classes

Type	Day	Start	End	Area
Lecture	Tuesday	09:00	09:50	KB
Lecture	Wednesday	09:00	09:50	KB
Lecture	Friday	09:00	09:50	KB

? Additional Class Information : 30 hours lectures + 6 hours tutorials, at times arranged.

Summary of Intended Learning Outcomes

At the end of this course students will be able to:
- discuss the chemistry and applications of a range of phosphorus, silicon, sulfur and selenium reagents in modern organic synthesis
- compare and contrast the biosynthesis of natural products with their chemical synthesis in the laboratory
- discuss the relative merits of solid phase and solution phase organic synthesis
- understand the role of solid phase organic synthesis in the pharmaceutical industry, particularly with respect to the use of combinatorial chemistry in screening against biological targets
- discuss the synthesis of various functional molecular architectures and the principles behind molecular switches, motors, shuttles and other 'designer' molecules
- apply Frontier Molecular Orbital (FMO) theory to predict the results of electrocyclic, cycloaddition and sigmatropic rearrangement processes
- compare and contrast mechanistic details of common modern synthetic organometallic reactions
- predict the outcome of some simple transition metal catalysed processes and comment on the strategies used by others for the synthesis of more complex targets