? Credit Points : 10  ? SCQF Level : 10  ? Acronym : BIO-4-BIsigtran

This topic will provide an overview of how signal transduction protein complexes transmit information via cell surface receptors, into the cytosol and into the nucleus. This will focus on the principal mechanisms of regulation between signalling molecules and on how they have evolved to allow the efficient transmission of messages via phosphorylation of proteins. The topic will focus on intracellular signalling through distinct classes of specific interaction domains in receptors, protein kinases and phosphatases which leads to the formation of signaling protein complexes. Some emphasis will be on the techniques by which novel signal transduction pathways are elucidated. This part will largely involve data interpretation by the participants. Assessment will be by examination and the penultimate session will include a practise run through old exam papers.

? Pre-requisites : Permission of the Curriculum Approval Officer.

? Costs : Notepads

Home subject area

Biochemistry, (School of Biological Sciences, Schedule K)

? Normal year taken : 4th year

? Delivery Period : Semester 2 (Blocks 3-4)

? Contact Teaching Time : 5 hour(s) 30 minutes per week for 5 weeks

First Class Information

Date Start End Room Area Additional Information 07/01/2008 09:00 11:00 Darwin Building - Room 615

All of the following classes

Type Day Start End Area Lecture Monday 09:00 10:50 KB Lecture Thursday 09:00 10:50 KB

Increased understanding of Biological processes. Detailed learning outcomes will be provided later.

Essay

The Course Secretary should be the first point of contact for all enquiries.

Course Secretary

Dr Matylda Sczaniecka
Tel : (0131 6)50 5454
Email : matylda.sczaniecka@ed.ac.uk

Course Organiser

Dr Jim Allan
Tel : (0131 6)50 5416
Email : J.Allan@ed.ac.uk

School Website : http://www.biology.ed.ac.uk/

College Website : http://www.scieng.ed.ac.uk/