Physical Chemistry in Action Level 11 (U01236)

? Credit Points : 20 ? SCQF Level : 11 ? Acronym : CHE-4-PCinAct11

A lecture course covering instruction in the theory and application of modern advanced instrumentation techniques to chemistry. The course comprises individual lectures courses on: Mass Spectrometry, Sensors, Microscopy and Imaging, and Biomolecular Systems. The course is suitable for Year 4/5 students on any Chemistry degree programme.

Entry Requirements

? Pre-requisites : Chemistry 3A and Chemistry 3B and Chemistry 3P Practical and Transferable Skills at a weighted average at or above Grade C at the first attempt (including Chemistry 3A and Chemistry 3B at a weighted average at or above Grade D), and Mathematics qualifications of at least 20 credits to level Applicable Mathematics 1 and Mathematical Methods 1; or with the permission of Head of School. Or CP Symmetry and Structure & CP Kinetics and Catalysis & CP Molecules and Matter & Electromagnetism and Optics & Physical Mathematics & Quantum Mechanics & Statistical Mechanics at a weighted average at or above Grade D, & CP Practical & Transferable Skills, & Electronic Methods in the Physical Laboratory , & Computational Methods , & Applicable Mathematics 3 , and Mathematical Methods 3 , & Foundations of Mathematical Physics 2. Or with permission of Head of School

? Prohibited combinations : Physical Chemistry in Action Level 10 (CHE-4-PCinAct10).

Subject Areas

Home subject area

Chemistry, (School of Chemistry, Schedule L)

Delivery Information

? Normal year taken : 4th year

? Delivery Period : Semester 2 (Blocks 3-4)

? Contact Teaching Time : 3 hour(s) per week for 10 weeks

First Class Information

Date	Start	End	Room	Area	Additional Information
07/01/2008	14:00	14:50	Lecture Theatre 100, Joseph Black Building	KB

All of the following classes

Type	Day	Start	End	Area
Lecture	Monday	14:00	14:50	KB
Lecture	Thursday	14:00	14:50	KB
Lecture	Friday	14:00	14:50	KB

? Additional Class Information : 30 hours lectures + 6 hours tutorials, at times arranged.

Summary of Intended Learning Outcomes

At the end of this course students will be able to:
- review the principles of different types of ion sources (including MALDI, electrospray ionisation, field and plasma ionisation and desorption), mass analysers (including quadrupole, ion-trap, time-of-flight, ion cyclotron and FT mass analysers), ion detectors and computer-aided data processing in modern mass spectrometry
- discuss novel techniques of mass spectroscopic analysis of proteins in a solvent free environment
- interpret fragmentation patterns, particularly as applied to peptide mass fingerprinting
- describe the essential elements of chemical sensors and rationalise the importance of factors such as sensitivity, selectivity, dynamic range, reproducibility, operating environment and cost
- illustrate examples of the chemical synthesis of specific molecular recognition systems and natural biosensor systems
- understand the physical principles of optical, electron and scanning probe microscopies, including confocal microscopy, scanning near field optical microscopy, electron microscopy, scanning tunnelling microscopy and atomic force microscopy
- illustrate example applications of fluorescence microscopy and imaging and in-situ microscopy studies of surface chemistry and catalysis
- understand thermodynamic and kinetic aspects of protein structure and dynamics
- rationalise the influence of the intracellular environment on the behaviour of macromolecules
- illustrate how modern analytical techniques are used to gain insight into the dynamics of the living cell with particular emphasis on the interactions between protein and DNA
Learning outcomes specific to attainment of a pass at Level 11 include:
- ability to integrate all, or most, of the main areas of the course
- development of original and creative responses to problems and issues within the course
- application of critical analysis, evaluation and synthesis to issues at the forefront of the subject area