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THE UNIVERSITY of EDINBURGHDEGREE REGULATIONS & PROGRAMMES OF STUDY 2007/2008
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Chemistry 3B (U00971)? Credit Points : 40 ? SCQF Level : 9 ? Acronym : CHE-3-B The course consists of lectures in Chemical Compounds: Synthesis Properties and Reactions. Topics to be covered include: reactive intermediates, targeted organic synthesis, organometallic chemistry, main group chemistry, heterocyclic chemistry, transition metal chemistry, medicinal chemistry, conformational analysis and stereoelectronic effects, reaction kinetics, organic reaction mechanisms, asymmetric synthesis, homogeneous catalysis, inorganic reaction mechanisms and biocatalysis. When taken in combination with Chemistry 3A and Chemistry 3P, this course forms part of the prescribed third year curriculum for students on degrees in Chemistry, Chemistry with Environmental Chemistry, and Medicinal and Biological Chemistry (including the With Industrial Experience, With Year in Europe, and With Management variants of these programmes). Entry Requirements? Pre-requisites : Chemistry 2 (CHE-2-Chem), and Applicable Mathematics 1, and Mathematical Methods 1; or with permission of Head of School ? Prohibited combinations : CP Kinetics and Catalysis (CHE-3-CPKinCat). Variants? This course has variants for part year visiting students, as follows
Subject AreasHome subject areaDelivery Information? Normal year taken : 3rd year ? Delivery Period : Full Year (Blocks 1-4) ? Contact Teaching Time : 5 hour(s) per week for 22 weeks First Class Information
All of the following classes
? Additional Class Information : Plus tutorials at times to be arranged Summary of Intended Learning Outcomes
At the end of this course students will be able to:
- Suggest syntheses of simple organic molecules from readily available starting materials using retrosynthetic analysis. - Understand the generation, detection and structure of important classes of neutral reactive intermediates, and know how they can be used in organic synthesis. - Show how the reactivity of heteroaromatic compounds is determined by the electronic effects of the heteroatom(s), and hence predict the reactivity of related structures. - Suggest synthetic routes to a range of 5- and 6-membered heterocyclic compounds via classical and modern methods. - Describe the chemistry of important classes of antibacterial agents and the basic principles of drug design. - Understand the factors which govern the structural chemistry of the main group elements. - Explain the electronic properties of the 2nd and 3rd row transition metals and how these properties influence the chemistry of these elements. - Predict the structure and reactivity of simple organometallic complexes, and understand how the chemistry of such complexes may be used and adapted to provide mechanisms for catalytic transformations. - Show proficiency in the quantitative analysis of kinetic data and the ability to relate a theoretical reaction mechanism to an experimentally determined rate law. - Understand the physical methods available for probing inorganic and organic reaction mechanisms and how these may be used in the elucidation of some fundamental reactions mechanisms. - Predict the shape of an organic molecule in three dimensions, and understand how the alignment of orbitals within a molecule controls reactivity. - Design enantioselective routes to organic target molecules using a range of modern methods for stereoselective synthesis. - Understand the basic concepts of biological catalysis by enzymes. Assessment Information
2 x 3 hour exams.
Exam times
Contact and Further InformationThe Course Secretary should be the first point of contact for all enquiries. Course Secretary Mrs Moira Wilson Course Organiser Dr Juan Mareque-Rivas School Website : http://www.chem.ed.ac.uk/ College Website : http://www.scieng.ed.ac.uk/ |
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