? Credit Points : 10  ? SCQF Level : 10  ? Acronym : BIO-4-BImacmoll

All macroscopic and cellular events have a cause on the molecular level. It is the properties of proteins and membranes, which determine their behaviour and, most frequently, their interactions with other proteins, cellular components and ligands. Therefore, a central aspect in structural biology as well as drug development is the characterisation and understanding of macromolecular properties and interactions. On the one hand, this leads to enhanced knowledge about molecular level mechanisms in health and disease, and on the other hand, certain properties of proteins can be used to monitor and assess their behaviour, e.g. in binding studies of pharmaceutical drugs to their target enzymes. We will look at some methods and techniques to probe macromolecular properties, especially biophysical methods and their applications to common problems. In practical sessions, we will use relevant computer software applications and design and perform an experiment on annexin loop motion.

? This course is not accepting further student enrolments.

? Pre-requisites : Permission of the Curriculum Approval Officer.

? Costs : Notepads

Home subject area

Biochemistry, (School of Biological Sciences, Schedule K)

? Normal year taken : 4th year

? Delivery Period : Semester 1 (Blocks 1-2)

? Contact Teaching Time : 2 hour(s) 45 minutes per week for 11 weeks

All of the following classes

Type Day Start End Area Lecture Monday 09:00 09:50 KB

Increased understanding of Biological processes. Detailed learning outcomes will be provided later.

Exam

The Course Secretary should be the first point of contact for all enquiries.

Course Secretary

Miss Emma Farrell
Tel : (0131 6)50 5470
Email : e.farrell@ed.ac.uk

Course Organiser

Dr Paul McLaughlin
Tel : (0131 6)50 7045/7060
Email : paul.mclaughlin@ed.ac.uk

School Website : http://www.biology.ed.ac.uk/

College Website : http://www.scieng.ed.ac.uk/