? Credit Points : 10  ? SCQF Level : 10  ? Acronym : BMS-4-PHnm1

The course will be organised and examined as a pair with Pharmacology of New Mediators B. The course deals with recent discoveries and methods of research and focuses on firstly lipid substances that include essential fatty acids (EFA) and substances derived from them biochemically, including cannabinoids and vanilloids. The roles of these substances in the immune system, mediation of pain perception and several other roles are considered. The importance of EFA lipids in the diet and in pathophysiology of various diseases are discussed and include the concept of oxidative stress contributing to disease Only a selected number of areas can be covered in the time available and these will include:

i. Importance of EFAs
ii. Products derived from EFAs.
iii. Non-enzymic conversion of EFAs to biologically active mediators as a marker of oxidative stress
iv. Phytocannabinoids and Endocannabinoids
v. Peroxisome Proliferator Activated Receptors
vi. Use of gene deletion in defining roles of 'orphan receptors'.

The course will consist of an introductory lecture and four discussion groups.

? This course is not available to visting students.

? Pre-requisites : Permission of the Curriculum Approval Officer. Pharmacology 3.

? Co-requisites : Pharmacology of New Mediators B.

? Prohibited combinations : Pharmacology of New Mediators U02582

Home subject area

Pharmacology (Biomedical Sciences), (School of Biomedical Sciences, Schedule T)

Other subject areas

Pharmacology (Biological Sciences), (School of Biological Sciences, Schedule K)

? Normal year taken : 4th year

? Delivery Period : Semester 1 (Blocks 1-2)

? Contact Teaching Time : 2 hour(s) 45 minutes per week for 11 weeks

First Class Information

Date Start End Room Area Additional Information 19/09/2006 10:00 12:00 Biomedical Seminar Room 6, Medical School, Teviot

All of the following classes

Type Day Start End Area Lecture Monday 09:00 12:00 Med+Vet

Increased undertanding of biological processes.
Detailed learningoutcomes will be provided later.

100% Written Examination.

The Course Secretary should be the first point of contact for all enquiries.

Course Secretary

Ms Caroline Morris
Tel : (0131 6)51 3255
Email : c.d.morris@ed.ac.uk

Course Organiser

Dr HJ Olverman
Tel : (0131 6)50 3523
Email : H.Olverman@ed.ac.uk

School Website : http://www.dbcls.med.ed.ac.uk/

College Website : http://www.mvm.ed.ac.uk/