THE UNIVERSITY of EDINBURGH

DEGREE REGULATIONS & PROGRAMMES OF STUDY 2005/2006
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Home : College of Science and Engineering : School of Biological Sciences (Schedule K) : Biochemistry

Archived Version

The Degree Regulations and Programmes of Study has been formulated as a dynamic online publication in order to provide the most up to date information possible. Master versions of the Degree Regulations and Programmes of Study incorporating all changes to date are archived twice a year on 1 September and within the first three University working days prior to the start of Semester 2 in January. Please note that some of the data recorded about this course has been amended since the last master version was archived. That version should be consulted to determine the changes made.

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Supercoiling in DNA and Chromatin (U00691)

? Credit Points : 10  ? SCQF Level : 10  ? Acronym : BIO-4-BIchrom

In both prokaryotic and eukaryotic cells, DNA is constrained into topologically sealed loops or domains. Under these circumstances DNA can become overtwisted or undertwisted (supercoiled) as a consequence of the binding of structural proteins or the actions of particular enzymes or enzyme complexes. Supercoiling can have profound effects on DNA structure, protein-DNA interactions, primary functions such as transcription and the regulation of the structural organisation of the genome during the cell cycle through the control of chromatin condensation. In this topic we shall consider how to describe the supercoiled state, the techniques available for measuring levels of supercoiling, the mechanisms by which the condition is regulated and the effects it has upon biological functions, particularly at the chromatin level in higher eukaryotes.

Entry Requirements

? Pre-requisites : Permission of the Curriculum Approval Officer.

? Costs : Notepads.

Subject Areas

Delivery Information

? Normal year taken : 4th year

? Delivery Period : Semester 1 (Blocks 1-2)

? Contact Teaching Time : 2 hour(s) 45 minutes per week for 11 weeks

First Class Information

Date Start End Room Area Additional Information
26/09/2005 14:00 15:50 Room 6.615, Darwin Building + Outhouses KB

All of the following classes

Type Day Start End Area
Lecture Monday 14:00 15:50 KB

Summary of Intended Learning Outcomes

Increased understanding of Biological processes. Detailed learning outcomes will be provided later.

Assessment Information

Exam

Exam times

Diet Diet Month Paper Code Paper Name Length
1ST December 1 - 2 hour(s)

Contact and Further Information

The Course Secretary should be the first point of contact for all enquiries.

Course Secretary

Dr Karine Coenen
Tel : (0131 6)50 8651
Email : K.Coenen@ed.ac.uk

Course Organiser

Dr Jim Allan
Tel : (0131 6)50 5416
Email : J.Allan@ed.ac.uk

School Website : http://www.biology.ed.ac.uk/

College Website : http://www.scieng.ed.ac.uk/

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